- Spirit Hunter: Death Mark II
- Spirit Hunters: Infinite Horde – v1.0.3443 (Release)
- Spirit Mancer: Demon Hunter Edition + 5 DLCs/Bonuses
- Spirit Oath – v1.4
- Spirit of the Island: Complete Edition – v2.1.0.2 + 2 DLCs
- Spirit of the North – Build 6112756 (Enhanced Edition Update)
- Spiritfall – v1.0.05
- Spiritfarer: Farewell Edition + Bonus Content
- Spiritless Ltd. – v1.06
- Splatoon 3 – v1.1.1 + Switch Emulators
- Splatter
- Splice + Windows 7 Fix
- Split Fiction + Online Multiplayer
- SpongeBob SquarePants: Battle for Bikini Bottom – Rehydrated – Rev. 603296 (Build 5204247 – June 23, 2020) + Multiplayer
- SpongeBob SquarePants: The Cosmic Shake – v1.0.2.0 + Costume Pack DLC
- SpongeBob SquarePants: The Patrick Star Game
- SPORE Collection – GOG DRM-free
- SPRAWL + Soundtrack Bundle – v1.4 + Bonus OST
- SPY×ANYA: Operation Memories – Deluxe Edition, v1.0.5 + 5 DLCs
- Spyro Reignited Trilogy
- Squad 51 vs. the Flying Saucers
- Squirrel with a Gun – v1.5.10.0
- Squirrelmageddon! – v894
- SRX: The Game
- Star Control: Origins – Galactic Edition – v1.62.366103 + All DLCs + Bonus OST
- Star Drift Evolution + Multiplayer
- Star Ocean: The Divine Force – v01.01 Build 23063 (Denuvoless) + All DLCs
- Star Ocean: The Last Hope – 4K & Full HD Remaster
- Star Ocean: The Second Story R, v1.10 (Denuvoless)
- Star Renegades – v1.5.1.0 + 5 DLCs + Bonus ArtBook
- Star Trek Prodigy: Supernova
- Star Trek: Infinite – Deluxe Edition, v1.0.0 (8788) + 4 DLCs/Bonuses
- Star Trek: Resurgence
- Star Trucker: Deluxe Bundle – v1.0.37.0 + 2 DLCs/Bonuses
- Star Valor – v2.0.0b
- Star Wars Jedi: Fallen Order: Deluxe Edition – v1.0.10.0 (11.08.2021, Denuvoless)
- STAR WARS Jedi: Survivor – Deluxe Edition, v1.0.0.11 (Patch 9/Denuvoless) + All DLCs + Bonus Soundtracks [Monkey/Turtle Repacks]
- STAR WARS: Battlefront (2015) – v1.0.7.64833 + 2 Bonus OSTs
- STAR WARS: Battlefront Classic Collection
- Star Wars: Battlefront II – v06.11.2019
- STAR WARS: Bounty Hunter
- STAR WARS: Dark Forces Remaster
- STAR WARS: Episode I: Jedi Power Battles
- Starcom: Unknown Space, v17344 (Kepler)
- StarCraft 2: The Trilogy
- StarCraft: Remastered – v1.23.9.10756
- StarCrawlers Chimera
- Stardew Valley – v1.6.0 Build 24079
- Stardiver
- StarDrive 2: Digital Deluxe Edition v1.0b