- Stranglehold – v1.1 GOG/31068
- Strategic Mind: Blitzkrieg
- Strategic Mind: Collection (The Pacific v3.08, Blitzkrieg v1.26, Spectre of Communism v1.10)
- Strategic Mind: Fight for Freedom
- Strategic Mind: Spectre of Communism
- Strategic Mind: Spirit of Liberty – v1.0.1
- Strategic Mind: The Pacific – v3.01
- Strawhart
- Stray Blade – Build 12682948 + Valley of Strays DLC
- Stray Gods: The Roleplaying Musical – Ultimate Setlist Bundle – v8863 + 5 DLCs/OSTs
- Stray Souls + Windows 7 Fix
- Stray: Soundtrack Edition – v1.5#368 Revision 26632 (Patch 4) + Bonus OST + Windows 7 Fix
- Straya
- Strayed Lights: Deluxe Edition, Build 11697504 + Bonus Content
- Street Fighter 30th Anniversary Collection
- Street Fighter V: Champion Edition – v7.010 + All DLCs/Bonus Content
- Street Outlaws 2: Winner Takes All
- Street Power Football – v1.0.12344.0
- Streets of Rage 4 – v.07-s r13031 + Mr. X Nightmare DLC
- Stretcher Men + Windows 7 Fix
- Strike Force 2: Terrorist Hunt – Enhanced Edition – v2.0.1
- Strike Force 3 – v1.1.0 + Windows 7 Fix
- Strike Force Heroes: Deluxe Edition – v1.23 + 4 DLCs/Bonuses
- Strike Team Gladius
- Strike Vector EX
- Stronghold: Definitive Edition + Multiplayer
- Stronghold: Warlords – v1.10.23892.D + 5 DLCs/Bonus Content
- Strongloween: The Escape
- Struggle F.O: Deluxe Pack – v1.0.1 + Bonus Content
- Stubbs the Zombie in Rebel Without a Pulse – 2021 Re-release + Windows 7 Fix
- STUFFED
- Sturmwind EX
- Styx: Shards of Darkness – v1.05 + DLC
- Submachine: Legacy – v1.0.17
- Submerged – v1.1/v1.1.1 (Hidden Visions update/HotFix) + OST
- Submerged: Hidden Depths
- Subnautica – v65786 + Soundtrack
- Subnautica: Below Zero – v1.0 Build 44290
- Subverse – v1.0 (Release)
- SubwaySim Hamburg + Windows 7 Fix
- Succubus With Guns – Build 13403147 + 2 DLCs
- SUCCUBUS: Ultimate Edition – Build 15112813 + 16 DLCs
- SuchArt: Genius Artist Simulator – v2.1.0.0 + 2 DLCs
- Sudden Strike 4: Day One Edition – v1.12.28520 + 4 DLCs
- Sugar Shack – v1.0.3-rev6153 + Windows 7 Fix
- Sugardew Island: Your Cozy Farm Shop – Supporter Bundle, v3781 + DLC
- Suicide Guy: The Lost Dreams – v1.03
- Suicide Squad: Kill the Justice League, v1.0.6.0 + Offline DLCs + CrackFix/EAC Bypass + Bonus Soundtrack
- Suikoden I & II HD Remaster: Gate Rune and Dunan Unification Wars – v1.0.2 + Special Item Pack DLC
- Sumerian Six